〖學(xué)習(xí)經(jīng)歷〗:1997年12月獲無(wú)錫輕工大學(xué)(現(xiàn)為江南大學(xué))發(fā)酵工程專業(yè)博士學(xué)位;1989年12月獲無(wú)錫輕工業(yè)學(xué)院(現(xiàn)為江南大學(xué))發(fā)酵工程專業(yè)碩士學(xué)位;1987年6月獲江蘇農(nóng)學(xué)院(現(xiàn)為揚(yáng)州大學(xué))農(nóng)產(chǎn)品加工與儲(chǔ)藏專業(yè)學(xué)士學(xué)位。
〖研究經(jīng)歷〗:2000年6月-2001年6月,香港科技大學(xué)博士后;2003年7月-2004年12月,美國(guó)夏威夷大學(xué)訪問科學(xué)家。
〖學(xué)術(shù)及社會(huì)兼職〗:Microbial Cell Factories副主編、Journal of the Science of Food and Agriculture副主編、Bioresource Technology編委。
【主講課程】
碩士研究生:發(fā)酵過程優(yōu)化與控制
碩士研究生(留學(xué)生):Advances in Fermentation Engineering
本科生:生化工程; 新生研討課
1. Yang Song, Jianghua Li, Hyun-dong Shin, Guocheng Du*, Long Liu*, Jian Chen. One-step biosynthesis of α-ketoisocaproate from L-leucine by an Escherichia coli whole-cell biocatalyst expressing an L-amino acid deaminase from Proteus vulgaris.Scientific Reports. 2015, 5: 12614.
2. Hou Ying, Hossain Gazi Sakir, Li Jianghua, Shin Hyun-dong, Liu Long*, Du Guocheng*. Production of phenylpyruvic acid from L-phenylalanine using an L-amino acid deaminase from Proteus mirabilis: Comparison of enzymatic and whole-cell biotransformation approaches.Applied Microbiology and Biotechnology. 2015, 99: 8391-8402.
3. Liu Long, Zhuge Xin, Li Jianghua, Shin Hyun-dong, Du Guocheng*, Chen Jian*. Improved production of propionic acid via combinational overexpression of glycerol dehydrogenase and malate dehydrogenase from Klebsiella pneumoniae in Propionibacterium jensenii.Applied and Environmental Microbiology. 2015, 81: 2256-2264.
4. Zhuge Xin, Li Jianghua, Shin Hyun-dong, Liu Long*, Du Guocheng*, Chen Jian. Improved propionic acid production with metabolically engineered Propionibacterium jensenii by an oxidoreduction potential-shift control strategy.Bioresource Technology.2015, 175: 606-612.
5. Liu Long, Guan Ningzi, Li Jianghua, Shin Hyun-dong, Du Guocheng*, Chen Jian. Developing GRAS strains as promising cell factories for the production of nutraceuticals by systems and synthetic biology approaches: Advances and prospects.Critical Reviews in Biotechnology.2015. In press. 10.3109/07388551.2015.1121461
6.Yang Y, Kang Z*, Zhou J, Chen J, Du G*. High-level expression and characterization of recombinant acid urease for enzymatic degradation of urea in rice wine.Applied Microbiology and Biotechnology. 2015, 99(1): 301-308.
7. Zhen Fang, Juan Zhang*, Baihong Liu, Guocheng Du*, Jian Chen. Enhancement of the catalytic efficiency and thermostability of Stenotrophomonas sp. keratinase KerSMD by domain exchange with KerSMF.Microbial Biotechnology. 2016, 9(1): 35–46.
8. Zhen Fang, Juan Zhang*, Baihong Liu, Guocheng Du*, Jian Chen. Insight into the substrate specificity of keratinase KerSMD from Stenotrophomonas maltophilia by site-directed mutagenesis studies in S1 pocket.RSC Advances. 2015, 5: 74953–74960.
9.Nestor Ishimwe, Eric B. Daliri, Byong H. Lee*, Fang Fang and Guocheng Du*. The perspective on cholesterol-lowering mechanisms of probiotics.Molecular Nutrition & Food Research. 2015,59(1):94-105.